if(ITK_WRAP_PYTHON)
  itk_python_expression_add_test(
    NAME
    itkAmoebaOptimizerv4PythonTest
    EXPRESSION
    "instance = itk.AmoebaOptimizerv4.New()")

  itk_python_expression_add_test(
    NAME
    itkCommandIterationUpdatev4PythonTest
    EXPRESSION
    "instance = itk.CommandIterationUpdatev4.New()")

  itk_python_expression_add_test(
    NAME
    itkExhaustiveOptimizerv4PythonTest
    EXPRESSION
    "instance = itk.ExhaustiveOptimizerv4.New()")

  itk_python_expression_add_test(
    NAME
    itkGradientDescentLineSearchOptimizerv4TemplatePythonTest
    EXPRESSION
    "instance = itk.GradientDescentLineSearchOptimizerv4Template.New()")

  itk_python_expression_add_test(
    NAME
    itkGradientDescentOptimizerv4PythonTest
    EXPRESSION
    "instance = itk.GradientDescentOptimizerv4.New()")

  itk_python_expression_add_test(
    NAME
    itkLBFGSBOptimizerv4PythonTest
    EXPRESSION
    "instance = itk.LBFGSBOptimizerv4.New()")

  itk_python_expression_add_test(
    NAME
    itkLBFGSOptimizerBasev4PythonTest
    EXPRESSION
    "instance = itk.LBFGSOptimizerBasev4.New()")

  # LBFGSOptimizerBaseHelperv4 is not wrapped with POINTER so cannot use .New()
  itk_python_expression_add_test(
    NAME
    itkLBFGSOptimizerBaseHelperv4PythonTest
    EXPRESSION
    "inst = itk.LBFGSOptimizerBaseHelperv4")

  itk_python_expression_add_test(
    NAME
    itkMultiGradientOptimizerv4TemplatePythonTest
    EXPRESSION
    "instance = itk.MultiGradientOptimizerv4Template.New()")

  itk_python_expression_add_test(
    NAME
    itkMultiStartOptimizerv4TemplatePythonTest
    EXPRESSION
    "instance = itk.MultiStartOptimizerv4Template.New()")

  itk_python_expression_add_test(
    NAME
    itkOnePlusOneEvolutionaryOptimizerv4PythonTest
    EXPRESSION
    "instance = itk.OnePlusOneEvolutionaryOptimizerv4.New()")

  itk_python_expression_add_test(
    NAME
    itkPowellOptimizerv4PythonTest
    EXPRESSION
    "instance = itk.PowellOptimizerv4.New()")

  itk_python_expression_add_test(
    NAME
    itkQuasiNewtonOptimizerv4TemplatePythonTest
    EXPRESSION
    "instance = itk.QuasiNewtonOptimizerv4Template.New()")

  itk_python_expression_add_test(
    NAME
    itkRegistrationParameterScalesFromIndexShiftPythonTest
    EXPRESSION
    "instance = itk.RegistrationParameterScalesFromIndexShift.New()")

  itk_python_expression_add_test(
    NAME
    itkRegistrationParameterScalesFromJacobianPythonTest
    EXPRESSION
    "instance = itk.RegistrationParameterScalesFromJacobian.New()")

  itk_python_expression_add_test(
    NAME
    itkRegistrationParameterScalesFromPhysicalShiftPythonTest
    EXPRESSION
    "instance = itk.RegistrationParameterScalesFromPhysicalShift.New()")

  itk_python_expression_add_test(
    NAME
    itkRegularStepGradientDescentOptimizerv4PythonTest
    EXPRESSION
    "instance = itk.RegularStepGradientDescentOptimizerv4.New()")

  itk_python_expression_add_test(
    NAME
    itkSingleValuedNonLinearVnlOptimizerv4PythonTest
    EXPRESSION
    "instance = itk.SingleValuedNonLinearVnlOptimizerv4.New()")
endif()